The University of Liverpool, in collaboration with the ILAE Big Data Commision have performed an international consensus exercise to define the most meaningful outcomes for interventional studies for adults with epilepsy.

The Problem 

In current epilepsy research, the choice of outcomes measured varies widely, particularly in clinical trials.  This difference in outcome measurement leads to research waste and difficulty combining and comparing results from different studies. Historically, it has been unclear whether the outcomes currently being measured in research are relevant to people with epilepsy. 

The EPSET study has used international consensus methods to define which outcomes are so important that they should always be measured in studies for adults with epilepsy. This is the EPSET Core Outcome Set (COS).